Efficacy and safety of anti-TNF agents in patients with enthesitis related arthritis
نویسندگان
چکیده
Background Approximately 5–15% of patients with juvenile idiopathic arthritis belong to a subcategory of enthesitis related arthritis (ERA), which is strongly associated with HLA-B27 and male gender. Recent investigations have suggested markedly low discontinuation rates of antitumour necrosis factor (anti-TNF) agents in those with ERA, in whom reports on long-term efficacy and safety of anti-TNFs are still few.
منابع مشابه
Efficacy of a second TNF blocker, when the first one failed, in patients with juvenile idiopathic arthritis (JIA)
Results Out of 60 JIA patients enrolled, 40 (37 f, 3 m) were evaluated: 10 systemic arthritis, 2 persistent oligoarthritis, 11 extended oligoarthritis, 9 RF negative polyarthritis, 4 RF positive polyarthritis, 1 ERA (enthesitis related arthritis), 3 psoriatic arthritis. With a standard Chi square model, we didn't find a significant difference in the ACR and DAS response rates between the first ...
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